Effect of daunorubicin on the growth of adenovirus.

نویسندگان

  • K F Shortridge
  • S Squires
چکیده

Treatment of adenovirus type 5-infected cells with daunorubicin (D) at a concentration of 0-05 ug/ml reduced the in vitro virus infectivity by six logs. Mature virus particles were not detected in extracts of D-treated cells by density gradient centrifugation and the low level of infectivity observed appeared to be due to free nucleoprotein. Virus components produced in the D-treated cells were not released into the extracellular phase.

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عنوان ژورنال:
  • The Journal of antimicrobial chemotherapy

دوره 3 2  شماره 

صفحات  -

تاریخ انتشار 1977